Global Immunology Course 2023
My personal lecture notes from the Global Immunology Course, from molecular bonding and antigen recognition to T/B cells, cancer immunology, and neuroimmunology.
These are my personal notes from the Global Immunology Course 2023 hosted by IISc. They are not verified by the course experts, I’ve done my best to check them, but errors are mine. Corrections are very welcome: pawar@mpi-magdeburg.mpg.de.
A two-week deep dive into immunology, from the physical chemistry underlying molecular recognition all the way to cancer immunology and neuroimmunology. The notes below follow the daily sessions; each links to a longer write-up.
Day 0 (i) · Molecular Bonding and pH in Immunology
Ionic, covalent, hydrogen and van der Waals bonding, and why pH matters for immune function.
10 Dec 2023Day 0 (ii) · Binding Energy and Antigen–Antibody Interactions
Binding energy, dissociation constants, and the antigen–antibody relationship.
11 Dec 2023Day 1 · Introduction to Immunology
Tissue barriers, defence components in circulation, and a short history of the field.
12 Dec 2023Day 2 · Innate Immunity: PRRs and Cytokines
Innate responses, pattern-recognition receptors, and an introduction to cytokines.
14 Dec 2023Day 4 · Macrophages and Dendritic Cells
The roles of macrophages and dendritic cells in the immune system.
15 Dec 2023Day 5 · Type-I IFNs, DCs and Antigen Processing
Type-I interferons, dendritic cells, MHC molecules, and antigen presentation.
16 Dec 2023Workshop · Flow Cytometry
A hands-on weekend workshop on flow cytometry.
18 Dec 2023Day 6 · Antigen Presentation, TCR and T-cell Activation
Antigen presentation continued; T-cell-receptor signalling and activation.
19 Dec 2023Day 7 · CD4/CD8 and Regulatory T Cells
CD4 and CD8 T cells, regulatory T cells, and immune regulation.
20 Dec 2023Day 8 · B Cells and Cancer Immunology
B-cell functions and an introduction to cancer immunology.
21 Dec 2023Day 9 · Autoimmunity
Mechanisms and implications of autoimmunity.
22 Dec 2023Day 10 · Cancer Immunology and Neuroimmunology
Cancer immunology and the immune–nervous-system interface.